Component Selection for Transfusion & Appropriate Usage

Red Cells

Date Posted	Subject
Oct. 11, 2011	How many facilities are practicing universal irradiation? -Revisited
Sept. 21, 2011	Using whole blood for pediatric cardiovascular surgeries ADDENDA Oct. 11
July 12, 2011	Transfusion support for patients undergoing extracorporeal ventricular support
Aug. 11, 2010	How many facilities are practicing universal irradiation? ADDENDA Dec. 23; Jan. 9, Feb. 23 & May 31, 2011
May 6, 2010	Update - irradiation of blood products for solid organ transplant recipients
Dec. 27, 2009	Routine use of saline washed RBCs for patients undergoing cardiac surgery ADDENDA Dec. 29
Sept. 19, 2008	Use of irradiated blood products for febrile neutropenic patients ADDENDA Sept. 29
Aug. 6, 2008	What red cell products are ECMO centers using by age (of RBC) and anticoagulant? ADDENDA Aug. 29
Mar. 27, 2008	Routine use of newer (fresher) RBC products ADDENDA Mar. 28, 30 & 31, Apr. 4, 15 & 22, May 2, June 2 & 13
June 4, 2007	When is it to appropriate to discontinue providing leukoreduced and irradiated cellular components for pediatric cardiac bypass patients after surgery? ADDENDA June 11
May 30, 2007	Provision of washed allogeneic packed RBCs for adult cardiovascular surgery ADDENDA June 5
May 13, 2007	Policies for providing red cells for trauma patients with multiple antibodies ADDENDA May 15, 22, 25 & 30
Oct. 26, 2006	How do Trauma Facilities limit use of uncrossmatched trauma blood?
Sept. 6, 2006	The use of saline washed RBCs versus premedications for patients with Sickle Cell Disease and occasional mild to moderate urticarial reactions. Should we treat the patient or treat the blood? ADDENDA Sept. 12
Aug. 24, 2006	Selection of Rh-positive RBC units for brain-dead Rh-negative individuals who are scheduled for organ harvest
June 6, 2006	Selection of donor RBCs for a patient with auto anti-e, but who is E-negative and e-positive ADDENDA June 6, 7, 8, 12 & 20
Apr. 4, 2006	Transfusion Trigger Trial for Functional Outcomes in Cardiovascular Patients Undergoing Surgical Hip Fracture Repair (FOCUS)
Sept. 9, 2005	Transfusion support of patients who require transplantation of ABO incompatible solid organs ADDENDA Sept. 10
Aug. 28, 2005	How long do indications for irradiated blood products continue for patients achieving a "cure" of the originally qualifying condition? ADDENDA Sept. 1
Aug. 28, 2005	Indications for selecting 'sickle negative' donor RBC units for transfusion ADDENDA Sept. 1 & 2
Aug. 3, 2005	Should irradiated blood products be used for patients receiving anti-Tumor Necrosis Factor (TNF) agents? ADDENDA Aug. 5
June 16, 2005	The case for limiting transfusions to ABO identical red cells/ platelets/ FFP/ cryoprecipitate and avoiding transfusion of incompatible cell associated or soluble antigen or isoagglutinins ADDENDA June 20, 22 & 23
April 7, 2005	Should CMV safe blood components be provided for transfusion to post-partum women?
Feb. 27, 2005	How do blood banks know when a patient should get irradiated blood, if the patient's doctor forgets to order the blood to be irradiated? ADDENDA Feb. 28; Mar. 1, 7 & 8, 2005; Apr. 17, 19, 21 & 23; May 25; June 16, 2006; Dec. 29, 2007; Jan. 10, 2008
Nov. 9, 2004	Switching from uncrossmatched type O to type-specific Red Cells in urgent bleeding situations ADDENDA Nov. 9, 23, 29 & Dec. 5; Dec. 12, 2007
Sept. 19, 2004	Irradiation of cellular blood products intended for patients with HIV/AIDS
Aug. 11, 2004	Whole blood for cardiac bypass surgery - how fresh should it be? ADDENDA Aug. 16 & 17
July 21, 2004	Automatic protocols for dealing with massive transfusion ADDENDA July 23 & 26, Aug. 2, 4, 5, 6, 11 & 18, Sept 22, Oct 31, Nov 9, Dec 5 & 18; June 26, July 3 & 16, 2008
May 6, 2004	The use of leukocyte-reduced components for liver transplant candidates/recipients ADDENDA May 11
Apr. 19, 2004	Is there a need to irradiate cellular products for transfusion to potential organ donors and those used for perfusion of harvested organs? ADDENDA Apr. 20
Apr. 19, 2004	In heart transplant patients receiving leukoreduced red cells is there evidence to support washing of the cells to remove soluble HLA antigens that might contribute to HLA alloimmunization and organ rejection? ADDENDA Apr. 23 & 25
Apr. 6, 2004	How prevalent is leukocyte reduction by filtration as a method of providing 'CMV-safe' components? ADDENDA Apr. 7, 8, 11 & 16
Oct 28, 2003	Is irradiation necessary for cellular blood products intended for patients receiving Fludarabine and/or similar drugs for low-grade non-Hodgkin's lymphoma? ADDENDA Nov. 10, 14, 24 & 26; Dec. 12 REACTIVATED Dec. 13
May 29, 2003	For preventing post-transfusion CMV, does recent data merit a reassessment of the equivalence of leukoreduction to use of seronegative donors? ADDENDA June 1 & 2
Jan. 23, 2003	Is it ever acceptable to intentionally transfuse ABO-incompatible RBCs? ADDENDA Jan. 24, 27, 28 & 29; Mar. 31
Nov. 12, 2002	Prestorage leukoreduction for prevention of transfusion-transmitted CMV infection - current AABB recommendations
Sept. 25, 2002	Should we worry about cold-reacting antibodies in patients undergoing hypothermia for cardiac surgery? (REVISITED) ADDENDA Nov. 21 & 26, Dec. 15; May 22, June 2 & Sept. 22, 2003; Sept 30, 2004; May 26, 2005; Jan. 12, 2009
Aug. 2, 2002	Should brain-dead persons whose organs qualify for harvesting and transplantation receive red cell transfusions to improve organ survival? ADDENDA Mar. 28, 2005
July 11, 2002	Selection of Red Cells for supporting Rh-positive recipients of Rh-negative marrow during and after engraftment ADDENDA July 13
June 24, 2002	When to use volume-reduced blood products for avoiding volume overload in patients at risk? ADDENDA June 24
May 23, 2002	Transfusion support with RBC and plateletpheresis units for patients who are post auto/-allo BMT or solid organ transplantation ADDENDA May 24
May 3, 2002	RBC transfusions for a patient with ITP who is receiving IV anti-D therapy ADDENDA May 3, 6 & 7
May 1, 2002	Transfusing donor RBC units obtained from individuals whose plasma contains unexpected antibodies ADDENDA May 2; Feb. 21, 2007; May 16 & June 25, 2008
April 13, 2002	Is it a safe practice to transfuse sickle trait donor RBC units to patients with sickle cell disease?
April 9, 2002	Should transfusion of thalassemia patients be managed using phenotype-matched RBC donor units? ADDENDA April 15
Jan. 22, 2002	Transfusion of patients who have paroxysmal nocturnal hemoglobinuria (PNH) ADDENDA Jan. 24
Dec. 7, 2001	Is it necessary to irradiate cellular blood products for patients undergoing cardiac surgery? ADDENDA Dec. 7 & 10; Sept. 19, 22 & 27, Nov 17 & 23, 2008
Nov. 6, 2001	Fresh Whole Blood - When is it warranted? ADDENDA Nov. 8 & 9; Feb. 14, Mar. 15 & 18, 2002; REACTIVATED Oct 14, 2004
Oct. 22, 2001	Use of phenotype-matched donor RBCs for transfusion of patients with sickle cell anemia ADDENDA Oct. 24 & 29; Feb 6, 2005; Apr. 4, 2006
Aug. 20, 2001	Strategies for STAT provision of blood for patients who bleed out in a cardiovascular OR and/or ICU ADDENDA Aug. 22
June 13, 2001	Should we irradiate Red Cells transfused to patients with sickle cell anemia? ADDENDA June 20, 2001
Dec. 23, 2000	Who considers leukoreduced cellular blood products equivalent to those made from CMV seronegative donors? ADDENDA Jan. 24 and Feb. 3, 2001
Jan. 9, 2000	When to Switch from Rh-neg. to Rh-pos. RBC in a Rapidly Bleeding Patient?
Nov. 4, 1999	Universal Leukoreduction - Hospital Viewpoints
Oct. 11, 1999	What are your policies for collection &/or transfusion of blood from donors with sickle cell trait? ADDENDA Nov. 11
Mar. 24, 1999	Should we worry about cold-reactive antibodies in cardiac surgery? ADDENDA Jan. 12, 2009

Plasma Components

Date Posted	Subject
Jan. 12, 2012	Use of liquid plasma for resuscitation of actively bleeding trauma patients
May 1, 2010	What is the practice regarding extending storage of thawed FP24 to 5 days?
Aug. 11, 2009	Plasma infusion instead of plasma exchange for maintenence of a remission in a patient with ADAMTS-13 synthetic defect causing relapsing TTP ADDENDA Aug. 18
May 23, 2009	Is darker-colored FFP safe to transfuse? ADDENDA May 26 & July 1
Jan. 14, 2007	Strategies for transfusion support of a patient with TAR (Thrombocytopenia Absent Radius) Syndrome ADDENDA Jan. 24
July 12, 2006	Provision of irradiated fresh frozen plasma ADDENDA July 18 & 28
May 4, 2006	What INR thresholds are being used for prophylactic and therapeutic use of FFP? ADDENDA May 7, 8, 15 & 23; July 2
Oct. 25, 2005	Is it appropriate to have separate transfusion guidelines for 'cardiac patients' and/or for those undergoing specific diagnostic or therapeutic procedures? ADDENDA Oct. 28 & Nov. 8
Oct. 17, 2005	Use of CMV serologically tested CMV negative FFP ADDENDA Oct. 19 & 21
Sept. 9, 2005	Transfusion support of patients who require transplantation of ABO incompatible solid organs ADDENDA Sept. 10
July 14, 2005	Routine use of cryoprecipitate to reverse prolonged protime and INR prior to heart surgery ADDENDA July 19 & 21; Aug. 10
June 16, 2005	The case for limiting transfusions to ABO identical red cells/ platelets/ FFP/ cryoprecipitate and avoiding transfusion of incompatible cell associated or soluble antigen or isoagglutinins ADDENDA June 20, 22 & 23
Mar. 21, 2005	Experience in the use of THAWED PLASMA ADDENDA Mar. 21, 22, 23 & Apr. 3; Mar. 1, 6, 7 & 17, 2007
Nov. 17, 2004	Risk of transfusing ABO-incompatible plasma to recipients of ABO-compatible bone marrow transplants ADDENDA Nov. 18 & 19
July 21, 2004	Automatic protocols for dealing with massive transfusion ADDENDA July 23 & 26, Aug. 2, 4, 5, 6, 11 & 18, Sept 22, Oct 31, Nov 9, Dec 5 & 18; June 26, July 3 & 16, 2008
Apr. 3, 2004	Restrictions to the use of thawed plasma versus FFP ADDENDA Apr. 5, 6 & 8
June 24, 2002	When to use volume-reduced blood products for avoiding volume overload in patients at risk? ADDENDA June 24
May 3, 1999	Some practical questions about donor retested FFP
Feb. 25, 1999	Selection of plasma after bone marrow transplantation

Platelets

Date Posted	Subject
Mar. 26, 2012	Is it always necessary to provide Rh(D) negative platelets to a patient with anti-D?
Feb. 21, 2012	Policy on transfusion of ABO incompatible platelets
Sept. 21, 2011	HLA matched platelets ADDENDA Sept. 30
Jan. 24, 2008	Handling platelet transfusions requests for patients with intracranial bleeds who are on Plavix®
Apr. 15, 2007	Are there data to support the practice of transfusing a 'trial' dose of platelets to patients with a presumptive diagnosis of ITP? ADDENDA Apr. 21 & 25
Jan. 14, 2007	Strategies for transfusion support of a patient with TAR (Thrombocytopenia Absent Radius) Syndrome ADDENDA Jan. 24
Feb. 26, 2006	Is there concern by transfusion medicine specialists that new guidelines for platelet donations may impact on the availability of platelets for transfusion? ADDENDA Feb. 27 & Mar. 1, 5 & 8
June 16, 2005	The case for limiting transfusions to ABO identical red cells/ platelets/ FFP/ cryoprecipitate and avoiding transfusion of incompatible cell associated or soluble antigen or isoagglutinins ADDENDA June 20, 22 & 23
Sept. 19, 2004	Irradiation of cellular blood products intended for patients with HIV/AIDS
July 21, 2004	Automatic protocols for dealing with massive transfusion ADDENDA July 23 & 26, Aug. 2, 4, 5, 6, 11 & 18, Sept 22, Oct 31, Nov 9, Dec 5 & 18; June 26, July 3 & 16, 2008
Mar. 24, 2004	Refusal to use Rh positive platelets for an Rh negative male undergoing coronary artery bypass surgery ADDENDA Mar. 25 & Apr. 3
Oct 28, 2003	Preoperative blood support for a patient with post-transfusion thrombocytopenic purpura
Nov. 4, 2002	Platelet transfusions during cardiothoracic surgery ADDENDA Nov. 26 & Dec. 6
June 24, 2002	When to use volume-reduced blood products for avoiding volume overload in patients at risk? ADDENDA June 24
May 23, 2002	Transfusion support with RBC and plateletpheresis units for patients who are post auto/-allo BMT or solid organ transplantation ADDENDA May 24
May 10, 2002	The practice of transfusing out-of-type platelets ADDENDA May 11, 13 & 14; Sept. 2, 8, 20 & 29; Oct. 3, Nov. 1 & 2, 2005
April 2, 2002	Reducing supernatant plasma of pooled platelets before administration to ABO-incompatible adult recipients ADDENDA April 3, 8 & 14
Oct. 25, 2001	Washed and volume-reduced Plateletpheresis units ADDENDA Oct. 25 & 27
Sept. 28, 2001	Rh immune globulin (RHIG) administration after transfusion of Rh-pos platelets/plateletpheresis units to Rh-neg recipients ADDENDA Sept. 28 & 29
July 18, 2001	Single Donor Platelets are associated with fewer Septic Reactions than Platelet Concentrates
June 21, 2001	How long should you wait after administering a dose of the platelet inhibitor Plavix (clopidogrel) before a patient may be transfused with platelets? ADDENDA June 27, 2001
Mar. 20, 2001	Usage of Pooled Platelets vs Pheresis Platelets
July 31, 2000	Transfusing Platelets to Patients Undergoing Dialysis - Wait Until Afterward?
July 12, 2000	Does platelet transfusion help patients who bleed while on the drug Reopro? ADDENDA July 18, 19 & 21

Other Products

Date Posted	Subject
Sept. 30, 2010	Protocol for off-label use of Factor VII?
July 24, 2009	Autologous platelet rich plasma injection for treatment of a torn tendon injury
July 14, 2009	Factor XI Concentrates ADDENDA July 21
Oct. 30, 2006	Published guidelines and standardized use of fibrin sealants and topical hemostatic agents ADDENDA Oct. 31, 2006
Oct. 11, 2004	Use and QC of 'platelet gel' ADDENDA Jan. 20, 2005; Feb. 1, 2005
Aug. 2, 2002	Should brain-dead persons whose organs qualify for harvesting and transplantation receive red cell transfusions to improve organ survival? ADDENDA Mar. 28, 2005
May 31, 2002	Updated information regarding 'Blood Substitutes' ADDENDA June 3 & 10
May 30, 2002	Emergency reversal of Warfarin effect - FFP or Prothrombin Complex Concentrate? ADDENDA May 31; Jan. 5, 6, 8, 9, 10, 13, 15, 17 & 24, 2006
Dec. 4, 2001	Risk of using topical bovine thrombin as a hemostatic agent during cardiovascular surgery ADDENDA Dec. 7

Guidelines & Monitoring of Transfusion Practice

Date Posted	Subject
May 4, 2012	Ethics of end of life transfusion
Jan. 6, 2012	Can a blood utilization/transfusion committee meet via email only?
Nov. 19, 2011	REACTIVATED DISCUSSION: Benchmarks in Transfusion Medicine
Oct. 31, 2011	In search of references for blood utilization review, including criteria for blood transfusions
July 22, 2011	Integration of the Surgical Blood Order Schedule into the hospital information system
Feb. 23, 2011	2009 WHO guidelines in the treatment of Dengue
Sept. 27, 2009	Blood product protocols for pediatric cardiac surgeries
Sept. 9, 2009	Standardized Transfusion Orders And Guideline Worksheet ADDENDA Sept. 16 & 27
May 3, 2009	Should surgical intensive care units be exempt from prospective review of transfusion practices? ADDENDA June 12
Feb. 26, 2009	CONTINUED DISCUSSION: Comments requested on Joint Commission meeting to determine the need to incorporate blood management performance measures into their survey and accreditation process ADDENDA Oct. 4 & Nov. 19
June 19, 2007	Testing to measure efficacy of a transfusion ADDENDA July 8
June 19, 2007	Standardizing transfusion appropriateness
Feb. 19, 2007	Comments requested on Joint Commission meeting to determine the need to incorporate blood management performance measures into their survey and accreditation process ADDENDA Feb. 20 & Mar. 17; July 25, 30 & 31, Aug. 12, 17, 21 & 22, 2008
Apr. 4, 2006	Transfusion Trigger Trial for Functional Outcomes in Cardiovascular Patients Undergoing Surgical Hip Fracture Repair (FOCUS)
Oct. 25, 2005	Is it appropriate to have separate transfusion guidelines for 'cardiac patients' and/or for those undergoing specific diagnostic or therapeutic procedures? ADDENDA Oct. 28 & Nov. 8
Oct. 25, 2005	Transfusion practice review for oncology patients
July 21, 2005	Blood usage during total hip replacements ADDENDA July 25 & 26
Mar. 28, 2005	Should there be arbitrary triggers for transfusing brain-dead potential organ donors? ADDENDA Mar. 29; REACTIVATED Oct. 3
Nov. 23, 2004	Integration of transfusion avoidance and conservation programs with Hospital Transfusion Committees ADDENDA Nov. 24 & 26
Nov. 18, 2004	Acceptability of conducting Utilization Review Committee meetings by e-mail ADDENDA Nov. 19
Dec. 8, 2003	Strategies to improve utilization of blood products by emergency room physicians
Oct 25, 2003	Guidelines for blood utilization/justification for transfusion ADDENDA Oct. 28 & 30
July 1, 2003	Recommended (or Maximum) Surgical Blood Order Schedules (RSBOS or MSBOS) for cardiac surgery ADDENDA July 2 & 3
Apr. 29, 2003	How well do clinicians document the reasons for their order to transfuse a patient? ADDENDA April 30, May 1, 2, 5 & 6; Apr. 24, May 13 & 25, June 1, 2007
Feb. 14, 2003	What percentage of red cells are transfused to oncology patients? ADDENDA Feb. 17 & 20
Oct. 9, 2002	Transfusion practices during and after reinfusion of blood salvaged during surgery
April 16, 2002	Are single unit red cell transfusions still considered 'suboptimal care'? ADDENDA April 17
April 8, 2002	Benchmark for blood use in open heart and valve replacement surgeries RESPONSES April 10 ADDENDA April 11
April 3, 2002	A call for "benchmark" data for peer review of blood utilization ADDENDA April 4 & 5; Mar 23, 29 & April 6, 2005; Oct. 12, 2008
Jan. 16, 2002	Recognition of patients who need special cellular products that are washed, irradiated, leukocyte-reduced and/or CMV negative ADDENDA Jan. 17, 21 & 30
Aug. 1, 2001	How should transfusion practices be monitored?
April 28, 2001	Questions on Cell Salvage During Cancer Surgery
Feb. 14, 2001	Should Transfusion Triggers for Autologous Transfusions Be More Liberal Than for Allogeneic Transfusions? ADDENDA Feb. 27 & Mar. 1, 2001
March 19, 2000	Two Audit Questions: 1. Upper Hb limit for transfusions? 2. Increasing compliance with Paul Gann Act?

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