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Induction of an inhibitor antibody to factor XI in a patient with severe inherited factor XI deficiency

A physician in Chicago has reviewed the report by Zucker M, et al and wonders if the induction of an inhibitor antibody to factor XI in a patient with severe inherited factor XI deficiency was caused by exposure to FXI present in fetal plasma rather than to FXI that was reportedly present in Rh immune globulin preparations?


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Ira A. Shulman, MD
CBBS e-Network Forum Editor & Moderator

W. Tait Stevens, MD
CBBS e-Network Forum Assistant Editor & Moderator

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Posted: November 27, 2007

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